Characterization of influenza A (H1N1) pdm09 viruses circulating in Mongolia
The Virology Laboratory, National Influenza Center(NIC), National Center for Communicable Diseases, MoH, Mongolia has received 2426 samples from sentinel surveillance sites 17 provinces and Ulaanbaatar city since start of 2015/2016 influenza season(week 40) until 7th week of 2016. The laboratory has tested all specimens by rt-RT-PCR, of which 297(12%) were positive for influenza; from them 267(89.9%) A(H1N1)pdm09, 3(1 %) A(H3N2) and 27(9 %) influenza type B were positive.
Please see weekly distribution number of influenza positive by subtype http://gamapserver.who.int/gareports/Default.aspx?ReportNo=1&CountryCode=MN
The 59 A(H1N1)pdm09 viruses which isolated in Mongolia characterized antigenically were similar to the vaccine virus A/California/07/2009(H1N1) by HI test. The B viruses are still in the process of antigenically and genetically characterised.
The Mongolian A(H1N1) pdm09 strains isolated in November and December 2015: A/Ulaanbaatar/3018/2015(H1N1)09pdm[ EPI709548]; A/Ulaanbaatar/2871/2015(H1N1)09pdm[EPI700846] are within the 6B subgroup defined by S162N and I216T substitutions in HA1(Figure 1).
Since October 1nd, 2015, 59 A(H1N1) pdm09 influenza strains tested by Virology Lab, NIC, Mongolia for antiviral resistance and all of them were sensitive to neuraminidase inhibitor oseltamivir.
Figure 1. Dendrogram of A/Ulaanbaatar/3018/2015(H1N1)pdm09; A/Ulaanbaatar/2871/2015(H1N1)pdm09 isolated in Nov, Dec 2015 compared with vaccine strains and other represented strains ( Mongolian strains are blue, Vaccine strain is red marked)
We cordially invite you to the 15th National Conference “Current Topics of Virology” which will be held on September 17, 2015 in Ulaanbaatar, Mongolia organized by the Mongolian Society of Virology, Mongolian Academy of Medical Science and other governmental and non-governmental organizations.
Please send your abstract by July 15, 2015 to the mail addresses:
as attachments to an e-mail-messages. The abstract has to be written in English and Mongolian in Times New Roman, 12 font within 200 words. In your e-mail message please indicate your desire for oral or poster presentation.
The Editorial Board of the Conference will contact you back by August 15, 2015 if your report will beselected for the oral presentation. The time allocated for the oral presentation is 10-15 minutes and it has to be accompanied by a slide presentation on PowerPoint (no more than 20 slides).
Hemagglutinin gene of the recent influenza A(H3N2) virus detected in Mongolia
The influenza virus detection started from 50th week of 2014 with A (H3N2) subtypes in Mongolia (A/Ulaanbaatar/4535/2014). We have sequenced HA gene of the newly detected A(H3N2) virus and the phylogenetic analyses has shown that A(H3N2) virus within clade 3C.3 (Picture 1).
Figure 1. Dendrogram of A/Ulaanbaatar/4535/2014 strain detected 50th week of 2014 compared with vaccine strains and clade represented strains ( Mongolian strains are green, Vaccine strain is red and clade represented strains are blue marked)